Paediatric Immunology is an important part of Immunology, which has a determinant role in Medicine. Inborn Errors of Immunity / Primary Immunodeficiency Diseases (PIDs) are caused by monogenic germline mutations that result in defect or dysfunction of the encoded protein. They predispose the immunodeficient persons to infections, allergy, autoimmunity - autoinflammatory and/or lymphohyperplasia, and they are at the core of Paediatric Immunology.
PIDs have a great biological impact and they have led to remarkable progress in understanding the components and functions of the complex immune system in humans and provide new diagnostic and therapeutic tools. Earlier recognition and better therapeutic management for patients with primary immunodeficiency disorders, as well as for the larger number of persons with immunocompomised conditions, contribute to improve quality of life of patients and their families and have a positive impact on society.
The purpose of this site is to disseminate information and education on the early and accurate diagnosis and proper treatment of Primary Immunodeficiencies and to promote public awareness of them, the Inborn Errors of Immunity.
Maria G. Kanariou
Paediatrician, Consultant in Paediatric Immunology
PhD, National and Kapodistrian University of Athens
Diploma in Immunology, University of London